PRODUCTS AND SERVICES

SCAD-MT cardiomyocyte

Cardiac microtissues for predictive drug discovery and development


SCAD-MT(TM) cardiomyocyte

SCAD-MT cardiomyocyte is a ready to use 3D microtissue device for the conduction of predictive cardiac toxicity, safety and efficacy assays. SCAD-MT cardiomyocyte is composed of human iPS cell-derived cardiomyocytes seeded on a nanofiber scaffold compatible with standard 96-well plates. SCAD-MT cardiomyocyte features highly matured, aligned and multi-layered myocardial microtissues with stable and significant dose-dependent drug responses.

SCAD-MT cardiomyocyte has been validated for several conventional cardiac cell evaluation methods, including multi-electrode array (MEA) and calcium transient methods from low to high levels of throughput.


Advantages

  1. Significant and stable drug responses
  2. Suitable for chronic studies
  3. Cell seeding and culturing is not required
  4. Compatibility with imaging techniques
  5. High throughput capability

SCAD-MT neuron

Neuronal microtissues for predictive drug discovery and development


SCAD-MT(TM) neuron

SCAD-MT neuron is a ready to use 3D microtissue device for the conduction of predictive neuronal toxicity, safety and efficacy assays. SCAD-MT neuron is composed of primary rat neurons or human iPS cell-derived neurons seeded on a nanofiber scaffold compatible with standard 96-well plates. SCAD-MT neuron features increased synaptic activities allowing stable and significant dose-dependent drug responses and the estimation of synaptic propagation velocities in MEA assays.

SCAD-MT neuron enables more efficient research workflows by reducing culturing times and preventing neuronal peeling and ensuing agglomeration common in 2D monolayer culturing approaches.


Advantages

  1. Elimination of neuronal peeling and agglomeration during culturing
  2. Stable long-term culture possible
  3. Increased synaptic activities
  4. Compatibility with imaging techniques
  5. High throughput capability

SCAD services

Enabling cell innovation through services


We understand how difficult it is for companies to prosper in the field of stem cells. SCAD offers a wide range of services aimed at enabling innovation in your stem cell businesses, including: (a) the development of iPS and embryonic stem cell generation and differentiation protocols; (b) the design and development of customized devices and culturing equipment; and (c) the development and evaluation of assays for drug toxicology, safety, and efficacy.



SCAD-MT(TM) cardiomyocyte

Supporting materials

Posters and publications (SCAD-MT cardiomyocyte)

  1. SPS2018: 3D-Cell Device with Aligned and Multilayered Myocardial Tissue Derived from iPS Cells for Predictive Drug Safety Applications -->
  2. Biomolecular Screenology 2018: 3D-Cell Device with Aligned and Multilayered Tissues for Predictive Drug Safety Applications -->

Posters and publications (SCAD-MT neuron)

  1. Biomolecular Screenology 2018: 3D-Cell Device with Aligned and Multilayered Tissues for Predictive Drug Safety Applications -->

Product datasheets

  • Download SCAD-MT cardiomyocyte datasheet(PDF) [2018.08]

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